The following video further describes the CC4CARB program:
Compounds synthesized within the CC4CARB program will be tested by NIAID under a separate contract for the minimum inhibitory concentrations (MICs) against select drug-resistant and wild type strains of Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, Staphylococcus aureus, and Neisseria gonorrhoeae.
Under the Scaffold Proposal header, we welcome the scientific community to submit ideas for antibiotic scaffolds to support this initiative.
Your Scaffold Proposal will be reviewed by an independent Scientific Advisory Board in conjunction with key persons at NIAID and RTI.
The external PI of an accepted proposal will be eligible for up to 10 hours of compensated time to help design and follow the progress of the compounds synthesized under their proposed scaffold.
If you wish to discuss your submission with an RTI team member, please email the project email address at CC4CARB@rti.org or call (833) 870-0484.
RTI shall preserve the confidentiality of proposals submitted to the center except where disclosure is required by law (Freedom of Information Act); however, compounds made from proposals submitted under CC4CARB will be publicly disclosed. See Proposal Confidentiality Policy.
The Chemistry Center for Combating Antibiotic Resistant Bacteria (CC4CARB) is a NIH NIAID lead initiative
contracted with RTI International. CC4CARB is a free service completely supported by NIH NIAID.